For the treatment of rheumatoid arthritis blockers of inflammatory cytokines are used for several years. Some natural substances such as the spicy substances of spices cause the same effect in vitro.
Such natural products have been linked to Nanocarriers and administered orally together with phase transfer catalysts (Oligouronide from brown algae) to humans, dogs and horses with rheumatic diseases. Besides the increase in lymphocyte proliferation, in all cases a significant improvement of the disease process was found.
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